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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C91723
http://purl.obolibrary.org/obo/NCIT_C91723
|
|---|---|
| Preferred Name | P-cadherin Antagonist PF-03732010 |
| Definitions |
An agent that inhibits P-cadherin (cdh3), with potential antineoplastic activity. PF-03732010 binds to and inhibits the activity of p-cadherin. Inhibition of the activity of p-cadherin may inhibit tumor cell invasion and proliferation in p-cadherin expressing tumor cells. P-cadherin, a cell-surface protein and member of the cadherin family, is overexpressed in a variety of solid tumors, and plays a role in cell adhesion, motility, invasion and proliferation.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An agent that inhibits P-cadherin (cdh3), with potential antineoplastic activity. PF-03732010 binds to and inhibits the activity of p-cadherin. Inhibition of the activity of p-cadherin may inhibit tumor cell invasion and proliferation in p-cadherin expressing tumor cells. P-cadherin, a cell-surface protein and member of the cadherin family, is overexpressed in a variety of solid tumors, and plays a role in cell adhesion, motility, invasion and proliferation. |
|---|---|
| prefLabel | P-cadherin Antagonist PF-03732010
|
| label | P-cadherin Antagonist PF-03732010
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| PDQ_Closed_Trial_Search_ID | 580366
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| code | C91723
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| prefixIRI | NCIT:C91723
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| in_subset | |
| Preferred_Name | P-cadherin Antagonist PF-03732010
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| FDA_UNII_Code | LPW79O1J5Z
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| Contributing_Source | FDA
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| Maps_To | P-cadherin Antagonist PF-03732010
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| CAS_Registry | 2070913-84-5
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| NCI_Drug_Dictionary_ID | 580366
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 580366
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| Semantic_Type | Pharmacologic Substance
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| UMLS_CUI | C3179737
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