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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C91700
http://purl.obolibrary.org/obo/NCIT_C91700
|
|---|---|
| Preferred Name | Oncolytic Newcastle Disease Virus MTH-68H |
| Definitions |
An oncolytic viral agent containing the oncolytic, live-attenuated strain of the paramyxovirus Newcastle disease virus (NDV), with potential antineoplastic activity. Upon administration, NDV MTH-68H specifically infects and replicates in cancer cells. This may result in a direct cytotoxic effect involving the lysis of tumor cells via apoptotic mechanisms and may eventually lead to an inhibition of cancer cell proliferation.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An oncolytic viral agent containing the oncolytic, live-attenuated strain of the paramyxovirus Newcastle disease virus (NDV), with potential antineoplastic activity. Upon administration, NDV MTH-68H specifically infects and replicates in cancer cells. This may result in a direct cytotoxic effect involving the lysis of tumor cells via apoptotic mechanisms and may eventually lead to an inhibition of cancer cell proliferation. |
|---|---|
| prefLabel | Oncolytic Newcastle Disease Virus MTH-68H
|
| label | Oncolytic Newcastle Disease Virus MTH-68H
|
| NCI_META_CUI | CL422080
|
| PDQ_Closed_Trial_Search_ID | 257613
|
| code | C91700
|
| prefixIRI | NCIT:C91700
|
| in_subset | |
| Preferred_Name | Oncolytic Newcastle Disease Virus MTH-68H
|
| Maps_To | Oncolytic Newcastle Disease Virus MTH-68H
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| NCI_Drug_Dictionary_ID | 257613
|
| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 257613
|
| Semantic_Type |
Pharmacologic Substance
Virus
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