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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C91407
http://purl.obolibrary.org/obo/NCIT_C91407
|
|---|---|
| Preferred Name | Piritrexim Isethionate |
| Definitions |
The isethionate salt of piritrexim, a synthetic antifolate agent with antiparasitic, antipsoriatic and antitumor properties. Piritrexim inhibits the enzyme dihydrofolate reductase enzyme, thereby disrupting folate metabolism and DNA synthesis and cell division.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | The isethionate salt of piritrexim, a synthetic antifolate agent with antiparasitic, antipsoriatic and antitumor properties. Piritrexim inhibits the enzyme dihydrofolate reductase enzyme, thereby disrupting folate metabolism and DNA synthesis and cell division. |
|---|---|
| prefLabel | Piritrexim Isethionate
|
| label | Piritrexim Isethionate
|
| code | C91407
|
| prefixIRI | NCIT:C91407
|
| in_subset | |
| Preferred_Name | Piritrexim Isethionate
|
| FDA_UNII_Code | V77I71FH72
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| Contributing_Source | FDA
|
| Chemical_Formula | C17H19N5O2.C2H6O4S
|
| Maps_To | Piritrexim Isethionate
|
| CAS_Registry | 79483-69-5
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| NSC Number | 351521
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| Has_Free_Acid_Or_Base_Form | |
| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type |
Organic Chemical
Pharmacologic Substance
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| UMLS_CUI | C1522061
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