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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C91390
http://purl.obolibrary.org/obo/NCIT_C91390
|
|---|---|
| Preferred Name | Rhenium Re-188 Ethiodized Oil |
| Definitions |
A rhenium (Re) 188 conjugate of ethiodized oil (lipiodol), an iodinated ethyl ester derived from poppy seed oil, with potential antineoplastic activity. Upon hepatic intra-arterial injection rhenium Re 188 ethiodized oil accumulates in hepatocellular carcinoma (HCC) tumor cells, thereby delivering a cytotoxic dose of radiation through Re 188 directly to the tumor cells. This may kill tumor cells while sparing surrounding normal cells and tissues. Compared to iodine I 131, Re 188 has a shorter half-life.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A rhenium (Re) 188 conjugate of ethiodized oil (lipiodol), an iodinated ethyl ester derived from poppy seed oil, with potential antineoplastic activity. Upon hepatic intra-arterial injection rhenium Re 188 ethiodized oil accumulates in hepatocellular carcinoma (HCC) tumor cells, thereby delivering a cytotoxic dose of radiation through Re 188 directly to the tumor cells. This may kill tumor cells while sparing surrounding normal cells and tissues. Compared to iodine I 131, Re 188 has a shorter half-life. |
|---|---|
| prefLabel | Rhenium Re-188 Ethiodized Oil
|
| label | Rhenium Re-188 Ethiodized Oil
|
| PDQ_Closed_Trial_Search_ID | 674326
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| code | C91390
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| prefixIRI | NCIT:C91390
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| in_subset | |
| Preferred_Name | Rhenium Re-188 Ethiodized Oil
|
| Maps_To | Rhenium Re-188 Ethiodized Oil
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| NCI_Drug_Dictionary_ID | 674326
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 674326
|
| Semantic_Type | Pharmacologic Substance
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| UMLS_CUI | C1530677
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