Id http://purl.obolibrary.org/obo/NCIT_C903
http://purl.obolibrary.org/obo/NCIT_C903
Preferred Name

Triaziquone

Definitions
An aziridinylbenzoquinone-based alkylating agent with potential antineoplastic activity. The alkylating group in triaziquone becomes activated upon reduction of quinone to the hydroquinone form. This eventually results in the alkylation and crosslinking of DNA, thereby inhibiting DNA replication followed by an induction of apoptosis. In addition, reactive oxygen species may form during redox cycling which may contribute to this agent's cytotoxic activity.
Type http://www.w3.org/2002/07/owl#Class
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