Preferred Name

Alpha-Synuclein
Synonyms
Definitions

Alpha-synuclein (140 aa, ~14 kDa) is encoded by the human SNCA gene. This protein plays a role in the modulation of presynaptic vesicle transport and release.

ID

http://purl.obolibrary.org/obo/NCIT_C90119

code

C90119

definition

Alpha-synuclein (140 aa, ~14 kDa) is encoded by the human SNCA gene. This protein plays a role in the modulation of presynaptic vesicle transport and release.

DesignNote

Peptides derived from alpha-synuclein are a major component of amyloid plaques in the brains of patients with Alzheimer's disease and non-amyloid aggregates in other synucleopathic neurodegenerative diseases.

label

Alpha-Synuclein

OMIM_Number

163890

Preferred_Name

Alpha-Synuclein

prefixIRI

NCIT:C90119

prefLabel

Alpha-Synuclein

Semantic_Type

Amino Acid, Peptide, or Protein

Swiss_Prot

P37840

UMLS_CUI

C1311196

subClassOf

http://purl.obolibrary.org/obo/NCIT_C16386

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