Biological and Environmental Research Ontology

Last uploaded: December 23, 2022

Id	http://purl.obolibrary.org/obo/NCIT_C895 http://purl.obolibrary.org/obo/NCIT_C895
Preferred Name	Chromomycin A3
Definitions	A glycosidic antineoplastic antibiotic isolated from the bacterium Streptomyces griseus. Chromomycin A3 reversibly binds to guanine-cytosine (G-C) base pairs in the minor groove of DNA, thereby inhibiting RNA synthesis. This agent is used as a fluorescent chromosome dye. (NCI04)
Type	http://www.w3.org/2002/07/owl#Class

definition	A glycosidic antineoplastic antibiotic isolated from the bacterium Streptomyces griseus. Chromomycin A3 reversibly binds to guanine-cytosine (G-C) base pairs in the minor groove of DNA, thereby inhibiting RNA synthesis. This agent is used as a fluorescent chromosome dye. (NCI04)
prefLabel	Chromomycin A3
label	Chromomycin A3
CHEBI_ID	CHEBI:34638
PDQ_Closed_Trial_Search_ID	39184
code	C895
prefixIRI	NCIT:C895
in_subset	http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C176424 http://purl.obolibrary.org/obo/NCIT_C128784 http://purl.obolibrary.org/obo/NCIT_C157711 http://purl.obolibrary.org/obo/NCIT_C157712 See more See less
Preferred_Name	Chromomycin A3
FDA_UNII_Code	DVW027E7NL
Contributing_Source	FDA
Chemical_Formula	C57H82O26
Maps_To	Chromomycin A3
CAS_Registry	7059-24-7
NSC Number	58514
NCI_Drug_Dictionary_ID	39184
Legacy Concept Name	Chromomycin_A3
type	http://www.w3.org/2002/07/owl#Class
Is_Value_For_GDC_Property	http://purl.obolibrary.org/obo/NCIT_C1909
subClassOf	http://purl.obolibrary.org/obo/NCIT_C2115 http://purl.obolibrary.org/obo/NCIT_C371
PDQ_Open_Trial_Search_ID	39184
Semantic_Type	Amino Acid, Peptide, or Protein Pharmacologic Substance Antibiotic
UMLS_CUI	C0040563

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