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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C88290
http://purl.obolibrary.org/obo/NCIT_C88290
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|---|---|
| Preferred Name | Short Chain Fatty Acid HQK-1004 |
| Definitions |
A short chain fatty acid (SCFA) with potential herpes simplex virus thymidine kinase gene (HSV-TK)-inducing activity. Upon administration, short chain fatty acid HQK-1004 may induce the expression of thymidine kinase (TK) by a silenced HSV-TK, which may activate a co-administered antiviral prodrug such as ganciclovir, resulting in the destruction of virally-infected cancer cells.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A short chain fatty acid (SCFA) with potential herpes simplex virus thymidine kinase gene (HSV-TK)-inducing activity. Upon administration, short chain fatty acid HQK-1004 may induce the expression of thymidine kinase (TK) by a silenced HSV-TK, which may activate a co-administered antiviral prodrug such as ganciclovir, resulting in the destruction of virally-infected cancer cells. |
|---|---|
| prefLabel | Short Chain Fatty Acid HQK-1004
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| label | Short Chain Fatty Acid HQK-1004
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| NCI_META_CUI | CL413539
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| PDQ_Closed_Trial_Search_ID | 657494
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| code | C88290
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| prefixIRI | NCIT:C88290
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| in_subset |
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| Display_Name | Short Chain Fatty Acid HQK-1004
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| Preferred_Name | Short Chain Fatty Acid HQK-1004
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| Contributing_Source | CTRP
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| Maps_To | Short Chain Fatty Acid HQK-1004
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| NCI_Drug_Dictionary_ID | 657494
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 657494
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| Semantic_Type |
Organic Chemical
Pharmacologic Substance
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