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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C88278
http://purl.obolibrary.org/obo/NCIT_C88278
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|---|---|
| Preferred Name | Multikinase Inhibitor SAR103168 |
| Definitions |
A multikinase inhibitor with potential antineoplastic activity. Upon intravenous infusion, multikinase inhibitor SAR103168 may, through the inhibition of multiple kinases, inhibit the phosphorylation and activation of signal transducer and activator of transcription 5 (STAT5). STAT5, a protein often upregulated in cancer cells, plays a key role in signal transduction pathways and the suppression of apoptosis.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A multikinase inhibitor with potential antineoplastic activity. Upon intravenous infusion, multikinase inhibitor SAR103168 may, through the inhibition of multiple kinases, inhibit the phosphorylation and activation of signal transducer and activator of transcription 5 (STAT5). STAT5, a protein often upregulated in cancer cells, plays a key role in signal transduction pathways and the suppression of apoptosis. |
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| prefLabel | Multikinase Inhibitor SAR103168
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| label | Multikinase Inhibitor SAR103168
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| PDQ_Closed_Trial_Search_ID | 656309
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| code | C88278
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| prefixIRI | NCIT:C88278
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| in_subset |
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| Display_Name | Multikinase Inhibitor SAR103168
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| Preferred_Name | Multikinase Inhibitor SAR103168
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| Contributing_Source | CTRP
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| Maps_To | Multikinase Inhibitor SAR103168
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| NCI_Drug_Dictionary_ID | 656309
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 656309
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| Semantic_Type | Pharmacologic Substance
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| UMLS_CUI | C2981800
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