Biological and Environmental Research Ontology

Last uploaded: December 23, 2022

Id	http://purl.obolibrary.org/obo/NCIT_C87767 http://purl.obolibrary.org/obo/NCIT_C87767
Preferred Name	Lebrikizumab
Definitions	A humanized monoclonal antibody against interleukin 13 (IL-13) with immunosuppressive and anti-asthmatic activities. Lebrikizumab binds to IL-13 and inhibits IL-13-mediated pathways. IL-13, a cytokine mainly secreted by type 2 helper T cells, plays a key role in the induction of allergic inflammation.
Type	http://www.w3.org/2002/07/owl#Class

definition	A humanized monoclonal antibody against interleukin 13 (IL-13) with immunosuppressive and anti-asthmatic activities. Lebrikizumab binds to IL-13 and inhibits IL-13-mediated pathways. IL-13, a cytokine mainly secreted by type 2 helper T cells, plays a key role in the induction of allergic inflammation.
prefLabel	Lebrikizumab
label	Lebrikizumab
code	C87767
Has_Target	http://purl.obolibrary.org/obo/NCIT_C20515
prefixIRI	NCIT:C87767
in_subset	http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C176424 http://purl.obolibrary.org/obo/NCIT_C116977 http://purl.obolibrary.org/obo/NCIT_C116978 http://purl.obolibrary.org/obo/NCIT_C128784 http://purl.obolibrary.org/obo/NCIT_C157711 http://purl.obolibrary.org/obo/NCIT_C157712 See more See less
Display_Name	Lebrikizumab
Preferred_Name	Lebrikizumab
FDA_UNII_Code	U9JLP7V031
Contributing_Source	CTRP FDA
Maps_To	Anti-IL-13 Humanized Monoclonal Antibody TNX-650
CAS_Registry	953400-68-5
NCI_Drug_Dictionary_ID	539362
Legacy Concept Name	Monoclonal_Antibody_TNX-650
type	http://www.w3.org/2002/07/owl#Class
Is_Value_For_GDC_Property	http://purl.obolibrary.org/obo/NCIT_C1909
subClassOf	http://purl.obolibrary.org/obo/NCIT_C20401 http://purl.obolibrary.org/obo/NCIT_C129822
Semantic_Type	Amino Acid, Peptide, or Protein Pharmacologic Substance Immunologic Factor
UMLS_CUI	C2981360

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