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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C87698
http://purl.obolibrary.org/obo/NCIT_C87698
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|---|---|
| Preferred Name | Mivobulin |
| Definitions |
A synthetic, colchicine analogue with potential antineoplastic activity. Mivobulin targets and binds to colchicine-binding site on tubulin, thereby inhibiting microtubule polymerization, the assembly of the mitotic spindle and mitosis. This eventually results in cell cycle arrest, apoptosis and a reduction in cellular proliferation.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A synthetic, colchicine analogue with potential antineoplastic activity. Mivobulin targets and binds to colchicine-binding site on tubulin, thereby inhibiting microtubule polymerization, the assembly of the mitotic spindle and mitosis. This eventually results in cell cycle arrest, apoptosis and a reduction in cellular proliferation. |
|---|---|
| prefLabel | Mivobulin
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| label | Mivobulin
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| code | C87698
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| prefixIRI | NCIT:C87698
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| in_subset | |
| Preferred_Name | Mivobulin
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| FDA_UNII_Code | 96U5LG549X
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| Contributing_Source | FDA
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| Chemical_Formula | C17H19N5O2
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| Maps_To | Mivobulin
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| CAS_Registry | 122332-18-7
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type | Pharmacologic Substance
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| UMLS_CUI | C2981335
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