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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C85466
http://purl.obolibrary.org/obo/NCIT_C85466
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|---|---|
| Preferred Name | Natural Killer Cells ZRx101 |
| Definitions |
A population of activated, immortalized, interleukin-2 (IL-2)-dependent, cytotoxic natural killer (NK) cells with potential antitumor activity. Natural killer cells ZRx101 are derived from NK-92 cells, having been modified to target tumor-associated antigens (TAAs) upregulated in certain types of cancer. The NK-92 cell line was originally isolated from a patient with large granular lymphocytic (LGL) leukemia/lymphoma.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A population of activated, immortalized, interleukin-2 (IL-2)-dependent, cytotoxic natural killer (NK) cells with potential antitumor activity. Natural killer cells ZRx101 are derived from NK-92 cells, having been modified to target tumor-associated antigens (TAAs) upregulated in certain types of cancer. The NK-92 cell line was originally isolated from a patient with large granular lymphocytic (LGL) leukemia/lymphoma. |
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| prefLabel | Natural Killer Cells ZRx101
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| label | Natural Killer Cells ZRx101
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| NCI_META_CUI | CL412341
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| PDQ_Closed_Trial_Search_ID | 643814
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| code | C85466
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| prefixIRI | NCIT:C85466
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| in_subset |
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| Display_Name | Natural Killer Cells ZRx101
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| Preferred_Name | Natural Killer Cells ZRx101
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| Contributing_Source | CTRP
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| Maps_To | Natural Killer Cells ZRx101
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| NCI_Drug_Dictionary_ID | 643814
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 643814
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| Semantic_Type |
Pharmacologic Substance
Cell
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