Link to this page
Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C834
http://purl.obolibrary.org/obo/NCIT_C834
|
|---|---|
| Preferred Name | Sodium Salicylate |
| Definitions |
The sodium salt of salicylic acid. As a nonsteroidal anti-inflammatory drug (NSAID), sodium salicylate irreversibly acetylates cyclooxygenases I and II, thereby inhibiting prostaglandin synthesis and associated inflammation and pain. This agent may also activate mitogen-activated protein kinase (p38MAPK), thereby inducing apoptosis in cancer cells. (NCI04)
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | The sodium salt of salicylic acid. As a nonsteroidal anti-inflammatory drug (NSAID), sodium salicylate irreversibly acetylates cyclooxygenases I and II, thereby inhibiting prostaglandin synthesis and associated inflammation and pain. This agent may also activate mitogen-activated protein kinase (p38MAPK), thereby inducing apoptosis in cancer cells. (NCI04) |
|---|---|
| prefLabel | Sodium Salicylate
|
| label | Sodium Salicylate
|
| PDQ_Closed_Trial_Search_ID | 43094
|
| code | C834
|
| prefixIRI | NCIT:C834
|
| in_subset | |
| Preferred_Name | Sodium Salicylate
|
| FDA_UNII_Code | WIQ1H85SYP
|
| Contributing_Source | FDA
|
| Chemical_Formula | C7H5O3.Na
|
| Maps_To | Sodium Salicylate
|
| CAS_Registry | 54-21-7
|
| NSC Number | 202167
|
| NCI_Drug_Dictionary_ID | 43094
|
| Legacy Concept Name | Sodium_Salicylate
|
| type | |
| ALT_DEFINITION | A drug that is a type of nonsteroidal anti-inflammatory drug. Sodium salicylate may be tolerated by people who are sensitive to aspirin.
|
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 43094
|
| Accepted_Therapeutic_Use_For | Fever; Inflammatory conditions; Pain
|
| Semantic_Type |
Organic Chemical
Pharmacologic Substance
|
| UMLS_CUI | C0037549
|
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |