Link to this page
Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C82362
http://purl.obolibrary.org/obo/NCIT_C82362
|
|---|---|
| Preferred Name | Innate Immunostimulator rBBX-01 |
| Definitions |
A recombinant 19 kDa protein derived from the Apicomplexa protozoan Eimeria with potential immunostimulating and antitumor activities. Upon administration, innate immunostimulator rBBX-01 activates dendritic cells (DCs), stimulates the Toll-like receptor 11 (TLR-11)-mediated release of interleukin-12 (Il-12) from DCs, and induces a T-helper 1 (Th1) type immune response, which may induce an immune response against tumor cells. Infection with Eimeria, a coccidian commonly infecting the intestine, may be negatively correlated with tumorigenesis.
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A recombinant 19 kDa protein derived from the Apicomplexa protozoan Eimeria with potential immunostimulating and antitumor activities. Upon administration, innate immunostimulator rBBX-01 activates dendritic cells (DCs), stimulates the Toll-like receptor 11 (TLR-11)-mediated release of interleukin-12 (Il-12) from DCs, and induces a T-helper 1 (Th1) type immune response, which may induce an immune response against tumor cells. Infection with Eimeria, a coccidian commonly infecting the intestine, may be negatively correlated with tumorigenesis. |
|---|---|
| prefLabel | Innate Immunostimulator rBBX-01
|
| label | Innate Immunostimulator rBBX-01
|
| NCI_META_CUI | CL408641
|
| PDQ_Closed_Trial_Search_ID | 640624
|
| code | C82362
|
| prefixIRI | NCIT:C82362
|
| in_subset |
See more
See less
|
| Display_Name | Innate Immunostimulator rBBX-01
|
| Preferred_Name | Innate Immunostimulator rBBX-01
|
| Contributing_Source | CTRP
|
| Maps_To | Innate Immunostimulator rBBX-01
|
| NCI_Drug_Dictionary_ID | 640624
|
| Legacy Concept Name | Innate_Immunostimulator_rBBX-01
|
| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 640624
|
| Semantic_Type | Pharmacologic Substance
|
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |