Link to this page
Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C82355
http://purl.obolibrary.org/obo/NCIT_C82355
|
|---|---|
| Preferred Name | Anti-CEA/Anti-HSG Bispecific Monoclonal Antibody TF2 |
| Definitions |
A tri-Fab bispecific monoclonal antibody (BiMoAb) divalent for the carcinoembryonic antigen (CEA) and monovalent for histamine-succinyl-glycine (HSG) peptide-hapten. Anti-CEA/anti-HSG bispecific monoclonal antibody TF2 binds to the tumor associated antigen (TAA) CEA on CEA-expressing tumor cells. Subsequently, an HSG peptide-hapten carrying a radionuclide is administered, binding to the anti-HSG binding fragment on the BiMoAb. Depending on the characteristics of the radionuclide used, CEA-expressing tumor cells may then be radioimaged and/or treated radioimmunotherapeutically.
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A tri-Fab bispecific monoclonal antibody (BiMoAb) divalent for the carcinoembryonic antigen (CEA) and monovalent for histamine-succinyl-glycine (HSG) peptide-hapten. Anti-CEA/anti-HSG bispecific monoclonal antibody TF2 binds to the tumor associated antigen (TAA) CEA on CEA-expressing tumor cells. Subsequently, an HSG peptide-hapten carrying a radionuclide is administered, binding to the anti-HSG binding fragment on the BiMoAb. Depending on the characteristics of the radionuclide used, CEA-expressing tumor cells may then be radioimaged and/or treated radioimmunotherapeutically. |
|---|---|
| prefLabel | Anti-CEA/Anti-HSG Bispecific Monoclonal Antibody TF2
|
| label | Anti-CEA/Anti-HSG Bispecific Monoclonal Antibody TF2
|
| NCI_META_CUI | CL408839
|
| PDQ_Closed_Trial_Search_ID | 639754
|
| code | C82355
|
| prefixIRI | NCIT:C82355
|
| in_subset | |
| Preferred_Name | Anti-CEA/Anti-HSG Bispecific Monoclonal Antibody TF2
|
| Maps_To | Anti-CEA/Anti-HSG Bispecific Monoclonal Antibody TF2
|
| NCI_Drug_Dictionary_ID | 639754
|
| Legacy Concept Name | Anti-CEA_Anti-HSG_Bispecific_Monoclonal_Antibody_TF2
|
| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 639754
|
| Semantic_Type |
Amino Acid, Peptide, or Protein
Immunologic Factor
|
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |