loading...| Preferred Name |
Pyridoxal Phosphate |
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| Synonyms |
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| Definitions |
The active form of vitamin B6 and a coenzyme for many pyridoxal phosphate (PLP)-dependent enzymes. PLP is involved in numerous enzymatic transamination, decarboxylation and deamination reactions; it is necessary for the synthesis of amino acids and amino acid metabolites, and for the synthesis and/or catabolism of certain neurotransmitters, including the conversion of glutamate into gamma-aminobutyric acid (GABA) and levodopa into dopamine. PLP can be used as a dietary supplement in cases of vitamin B6 deficiency. Reduced levels of PLP in the brain can cause neurological dysfunction. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C81627 |
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| CAS_Registry |
41468-25-1 |
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| Chemical_Formula |
C8H10NO6P.H2O |
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| code |
C81627 |
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| Contributing_Source |
FDA |
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| definition |
The active form of vitamin B6 and a coenzyme for many pyridoxal phosphate (PLP)-dependent enzymes. PLP is involved in numerous enzymatic transamination, decarboxylation and deamination reactions; it is necessary for the synthesis of amino acids and amino acid metabolites, and for the synthesis and/or catabolism of certain neurotransmitters, including the conversion of glutamate into gamma-aminobutyric acid (GABA) and levodopa into dopamine. PLP can be used as a dietary supplement in cases of vitamin B6 deficiency. Reduced levels of PLP in the brain can cause neurological dysfunction. |
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| FDA_UNII_Code |
5V5IOJ8338 |
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| in_subset | ||
| label |
Pyridoxal Phosphate |
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| Legacy Concept Name |
Pyridoxal_Phosphate |
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| NCI_Drug_Dictionary_ID |
804854 |
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| Preferred_Name |
Pyridoxal Phosphate |
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| prefixIRI |
NCIT:C81627 |
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| prefLabel |
Pyridoxal Phosphate |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C0034266 |
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| subClassOf |