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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C80868
http://purl.obolibrary.org/obo/NCIT_C80868
|
|---|---|
| Preferred Name | Falnidamol |
| Definitions |
A pyrimido-pyrimidine with antitumor activity. BIBX 1382 inhibits the intracellular tyrosine kinase domain of the Epidermal Growth Factor Receptor (EGFR) thus specifically reversing the aberrant enzymatic activity from overexpressed and constitutively activated EGFR, and subsequently inhibiting cell proliferation and inducing cell differentiation.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A pyrimido-pyrimidine with antitumor activity. BIBX 1382 inhibits the intracellular tyrosine kinase domain of the Epidermal Growth Factor Receptor (EGFR) thus specifically reversing the aberrant enzymatic activity from overexpressed and constitutively activated EGFR, and subsequently inhibiting cell proliferation and inducing cell differentiation. |
|---|---|
| prefLabel | Falnidamol
|
| label | Falnidamol
|
| code | C80868
|
| Has_Target | |
| prefixIRI | NCIT:C80868
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| in_subset | |
| Preferred_Name | Falnidamol
|
| FDA_UNII_Code | 0MU316797D
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| Contributing_Source | FDA
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| Chemical_Formula | C18H19ClFN7
|
| Maps_To | EGFR Inhibitor BIBX 1382
|
| CAS_Registry | 196612-93-8
|
| NCI_Drug_Dictionary_ID | 43568
|
| Legacy Concept Name |
BIBX_1382
Falnidamol
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| type | |
| ALT_DEFINITION | A drug that may inhibit tumor cells from multiplying. It is being studied for its ability to treat cancer.
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| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type |
Organic Chemical
Pharmacologic Substance
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| UMLS_CUI | C2825367
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