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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C80443
http://purl.obolibrary.org/obo/NCIT_C80443
|
|---|---|
| Preferred Name | Degarelix Acetate |
| Definitions |
The acetate form of a long-acting, synthetic peptide with gonadotrophin-releasing hormone (GnRH) antagonistic properties. Degarelix targets and blocks GnRH receptors located on the surfaces of gonadotroph cells in the anterior pituitary, thereby reducing secretion of luteinizing hormone (LH) by pituitary gonadotroph cells and so decreasing testosterone production by interstitial (Leydig) cells in the testes.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | The acetate form of a long-acting, synthetic peptide with gonadotrophin-releasing hormone (GnRH) antagonistic properties. Degarelix targets and blocks GnRH receptors located on the surfaces of gonadotroph cells in the anterior pituitary, thereby reducing secretion of luteinizing hormone (LH) by pituitary gonadotroph cells and so decreasing testosterone production by interstitial (Leydig) cells in the testes. |
|---|---|
| prefLabel | Degarelix Acetate
|
| label | Degarelix Acetate
|
| code | C80443
|
| Has_Target | |
| prefixIRI | NCIT:C80443
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| in_subset |
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| Display_Name | Degarelix Acetate
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| Preferred_Name | Degarelix Acetate
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| FDA_UNII_Code | I18S89P20R
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| Contributing_Source |
CTRP
FDA
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| Chemical_Formula | C82H103ClN18O16.C2H4O2.H2O
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| Maps_To | Degarelix Acetate
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| CAS_Registry | 934246-14-7
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| Legacy Concept Name | Degarelix_Acetate
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| Has_Free_Acid_Or_Base_Form | |
| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Accepted_Therapeutic_Use_For | advanced prostate cancer
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| Semantic_Type | Pharmacologic Substance
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| UMLS_CUI | C2718533
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| Delete | Subject | Author | Type | Created |
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