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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C79795
http://purl.obolibrary.org/obo/NCIT_C79795
|
|---|---|
| Preferred Name | Anti-Ganglioside GM2 Monoclonal Antibody BIW-8962 |
| Definitions |
A humanized anti-ganglioside GM2 (GM2) monoclonal antibody with potential antineoplastic and immunomodulating activities. Upon administration, anti-ganglioside GM2 monoclonal antibody BIW-8962 may activate an antibody dependent cellular cytotoxicity (ADCC) against GM2-expressing tumor cells. GM2 is a tumor associated antigen (TAA) overexpressed on the surface of many cancer cells, such as multiple myeloma (MM) cells and neuroblastoma cells.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A humanized anti-ganglioside GM2 (GM2) monoclonal antibody with potential antineoplastic and immunomodulating activities. Upon administration, anti-ganglioside GM2 monoclonal antibody BIW-8962 may activate an antibody dependent cellular cytotoxicity (ADCC) against GM2-expressing tumor cells. GM2 is a tumor associated antigen (TAA) overexpressed on the surface of many cancer cells, such as multiple myeloma (MM) cells and neuroblastoma cells. |
|---|---|
| prefLabel | Anti-Ganglioside GM2 Monoclonal Antibody BIW-8962
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| label | Anti-Ganglioside GM2 Monoclonal Antibody BIW-8962
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| PDQ_Closed_Trial_Search_ID | 618862
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| code | C79795
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| Has_Target | |
| prefixIRI | NCIT:C79795
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| in_subset |
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| Display_Name | Anti-Ganglioside GM2 Monoclonal Antibody BIW-8962
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| Preferred_Name | Anti-Ganglioside GM2 Monoclonal Antibody BIW-8962
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| Contributing_Source | CTRP
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| Maps_To | Anti-Ganglioside GM2 Monoclonal Antibody BIW-8962
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| NCI_Drug_Dictionary_ID | 618862
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| Legacy Concept Name | Anti-Ganglioside_GM2_Monoclonal_Antibody_BIW-896
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 618862
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| Semantic_Type |
Amino Acid, Peptide, or Protein
Immunologic Factor
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| UMLS_CUI | C2703163
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