Biological and Environmental Research Ontology

Last uploaded: December 23, 2022

Id	http://purl.obolibrary.org/obo/NCIT_C78863 http://purl.obolibrary.org/obo/NCIT_C78863
Preferred Name	Camsirubicin
Definitions	A synthetic non-cardiotoxic analogue of the anthracycline antibiotic doxorubicin with potential antineoplastic activity. Camsirubicin intercalates DNA and impedes the activity of topoisomerase II, inducing single and double-stranded breaks in DNA; inhibiting DNA replication and/or repair, transcription, and protein synthesis; and activating tumor cell apoptosis.
Type	http://www.w3.org/2002/07/owl#Class

definition	A synthetic non-cardiotoxic analogue of the anthracycline antibiotic doxorubicin with potential antineoplastic activity. Camsirubicin intercalates DNA and impedes the activity of topoisomerase II, inducing single and double-stranded breaks in DNA; inhibiting DNA replication and/or repair, transcription, and protein synthesis; and activating tumor cell apoptosis.
prefLabel	Camsirubicin
label	Camsirubicin
PDQ_Closed_Trial_Search_ID	601485
code	C78863
prefixIRI	NCIT:C78863
in_subset	http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C176424 http://purl.obolibrary.org/obo/NCIT_C116977 http://purl.obolibrary.org/obo/NCIT_C116978 http://purl.obolibrary.org/obo/NCIT_C128784 http://purl.obolibrary.org/obo/NCIT_C157711 http://purl.obolibrary.org/obo/NCIT_C157712 See more See less
Display_Name	Camsirubicin
Preferred_Name	Camsirubicin
FDA_UNII_Code	VI79RD8VNN
Contributing_Source	CTRP FDA
Maps_To	Camsirubicin
CAS_Registry	236095-26-4
NCI_Drug_Dictionary_ID	601485
Legacy Concept Name	Anthracycline_Analogue_GPX-150
type	http://www.w3.org/2002/07/owl#Class
Is_Value_For_GDC_Property	http://purl.obolibrary.org/obo/NCIT_C1909
subClassOf	http://purl.obolibrary.org/obo/NCIT_C1594
PDQ_Open_Trial_Search_ID	601485
Semantic_Type	Pharmacologic Substance
UMLS_CUI	C2698125

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