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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C787
http://purl.obolibrary.org/obo/NCIT_C787
|
|---|---|
| Preferred Name | Puromycin |
| Definitions |
An aminoglycoside antibiotic isolated from the bacterium Streptomyces alboniger. Acting as an analog of the 3' terminal end of aminoacyl-tRNA, puromycin incorporates itself into a growing polypeptide chain and causes its premature termination, thereby inhibiting protein synthesis. This agent has antimicrobial, antitrypanosomal, and antineoplastic properties; it is used as an antibiotic in cell culture. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An aminoglycoside antibiotic isolated from the bacterium Streptomyces alboniger. Acting as an analog of the 3' terminal end of aminoacyl-tRNA, puromycin incorporates itself into a growing polypeptide chain and causes its premature termination, thereby inhibiting protein synthesis. This agent has antimicrobial, antitrypanosomal, and antineoplastic properties; it is used as an antibiotic in cell culture. (NCI04) |
|---|---|
| prefLabel | Puromycin
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| label | Puromycin
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| Has_Salt_Form | |
| CHEBI_ID | CHEBI:17939
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| code | C787
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| prefixIRI | NCIT:C787
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| in_subset | |
| Preferred_Name | Puromycin
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| FDA_UNII_Code | 4A6ZS6Q2CL
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| Contributing_Source | FDA
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| Chemical_Formula | C22H29N7O5
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| Maps_To | Puromycin
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| CAS_Registry | 53-79-2
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| NSC Number | 3055
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| Legacy Concept Name | Puromycin
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type |
Pharmacologic Substance
Nucleic Acid, Nucleoside, or Nucleotide
Antibiotic
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| UMLS_CUI | C0034145
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