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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C77333
http://purl.obolibrary.org/obo/NCIT_C77333
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|---|---|
| Preferred Name | Abiraterone |
| Definitions |
A steroidal compound with antiandrogen activity. Abiraterone inhibits the enzymatic activity of steroid 17alpha-monooxygenase (17alpha-hydrolase/C17,20 lyase complex; CYP17A1), a member of the cytochrome p450 family that catalyzes the 17alpha-hydroxylation of steroid intermediates involved in testosterone synthesis. Administration of this agent may suppress testosterone production by both the testes and the adrenals to castrate-range levels.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A steroidal compound with antiandrogen activity. Abiraterone inhibits the enzymatic activity of steroid 17alpha-monooxygenase (17alpha-hydrolase/C17,20 lyase complex; CYP17A1), a member of the cytochrome p450 family that catalyzes the 17alpha-hydroxylation of steroid intermediates involved in testosterone synthesis. Administration of this agent may suppress testosterone production by both the testes and the adrenals to castrate-range levels. |
|---|---|
| prefLabel | Abiraterone
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| label | Abiraterone
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| Has_Salt_Form | |
| code | C77333
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| Has_Target | |
| prefixIRI | NCIT:C77333
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| in_subset |
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| Display_Name | Abiraterone
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| Preferred_Name | Abiraterone
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| FDA_UNII_Code | G819A456D0
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| Contributing_Source |
CTRP
FDA
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| Chemical_Formula | C24H31NO
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| Maps_To | Abiraterone
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| CAS_Registry | 154229-19-3
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| Legacy Concept Name | Abiraterone
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type | Pharmacologic Substance
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| UMLS_CUI | C0754011
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