Biological and Environmental Research Ontology

Last uploaded: December 23, 2022
Id http://purl.obolibrary.org/obo/NCIT_C77064
http://purl.obolibrary.org/obo/NCIT_C77064
Preferred Name

Cevipabulin
Definitions
A synthetic, water soluble tubulin-binding agent with potential antineoplastic activity. Cevipabulin appears to bind at the vinca-binding site on tubulin, but seems to act more similar to taxane-site binding agents in that it enhances tubulin polymerization and does not induce tubulin depolymerization. The disruption in microtubule dynamics may eventually inhibit cell division and reduce cellular growth.
Type http://www.w3.org/2002/07/owl#Class

All Properties

definition

A synthetic, water soluble tubulin-binding agent with potential antineoplastic activity. Cevipabulin appears to bind at the vinca-binding site on tubulin, but seems to act more similar to taxane-site binding agents in that it enhances tubulin polymerization and does not induce tubulin depolymerization. The disruption in microtubule dynamics may eventually inhibit cell division and reduce cellular growth.
prefLabel
Cevipabulin
label
Cevipabulin
Has_Salt_Form
code
C77064
prefixIRI
NCIT:C77064
in_subset
Preferred_Name
Cevipabulin
FDA_UNII_Code
P14M0DWS2J
Contributing_Source
FDA
Chemical_Formula
C18H18ClF5N6O
Maps_To
Cevipabulin
CAS_Registry
849550-05-6
Legacy Concept Name
Cevipabulin
type
Is_Value_For_GDC_Property
subClassOf
Semantic_Type
Pharmacologic Substance
UMLS_CUI
C2699167
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