Preferred Name | Cefaclor Anhydrous | |
Synonyms |
|
|
Definitions |
The anhydrous form of cefaclor, a beta-lactam, second-generation cephalosporin with antibacterial activity. Cefaclor binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis. |
|
ID |
http://purl.obolibrary.org/obo/NCIT_C76033 |
|
CAS_Registry |
53994-73-3 |
|
CHEBI_ID |
CHEBI:3478 |
|
Chemical_Formula |
C15H14ClN3O4S |
|
code |
C76033 |
|
Contributing_Source |
FDA |
|
definition |
The anhydrous form of cefaclor, a beta-lactam, second-generation cephalosporin with antibacterial activity. Cefaclor binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis. |
|
FDA_UNII_Code |
3Z6FS3IK0K |
|
in_subset | ||
label |
Cefaclor Anhydrous |
|
Legacy Concept Name |
Cefaclor_Anhydrous |
|
Preferred_Name |
Cefaclor Anhydrous |
|
prefixIRI |
NCIT:C76033 |
|
prefLabel |
Cefaclor Anhydrous |
|
Semantic_Type |
Pharmacologic Substance |
|
UMLS_CUI |
C2699131 |
|
subClassOf |
Delete | Mapping To | Ontology | Source |
---|---|---|---|
http://purl.bioontology.org/ontology/SNOMEDCT/785689005 | SNOMEDCT | LOOM | |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C76033 | NCIT | LOOM | |
http://purl.bioontology.org/ontology/RXNORM/1450910 | RXNORM | LOOM |