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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Enoxaparin Sodium | |
| Synonyms |
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| Definitions |
The sodium salt of enoxaparin, a low molecular weight, synthetic heparin. As an anticoagulant/antithrombotic agent, enoxaprin's mechanism of action is similar to that of heparin, although it exhibits a higher ratio of anti-Factor Xa to anti-Factor IIa activity. This agent also has anti-inflammatory properties, inhibiting monocyte adhesion to tumor necrosis factor alpha- or lipopolysaccharide-activated endothelial cells. Compared to unfractionated heparins, the use of enoxaparin is associated with lower incidences of osteoporosis and heparin-induced thrombocytopenia. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C75769 |
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| CAS_Registry |
679809-58-6
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|
| Chemical_Formula |
(C14H17NNaO11)n.C14H17NO11.C12H15NO12S.(C12H14NNa2O13S)n.C12H14NO13S.10Na.5O3S.H
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|
| code |
C75769
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| Contributing_Source |
FDA
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|
| definition |
The sodium salt of enoxaparin, a low molecular weight, synthetic heparin. As an anticoagulant/antithrombotic agent, enoxaprin's mechanism of action is similar to that of heparin, although it exhibits a higher ratio of anti-Factor Xa to anti-Factor IIa activity. This agent also has anti-inflammatory properties, inhibiting monocyte adhesion to tumor necrosis factor alpha- or lipopolysaccharide-activated endothelial cells. Compared to unfractionated heparins, the use of enoxaparin is associated with lower incidences of osteoporosis and heparin-induced thrombocytopenia.
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| FDA_UNII_Code |
8NZ41MIK1O
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|
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C173383 |
|
| label |
Enoxaparin Sodium
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|
| Legacy Concept Name |
Enoxaparin_Sodium
|
|
| NCI_Drug_Dictionary_ID |
37880
|
|
| PDQ_Closed_Trial_Search_ID |
37880
|
|
| PDQ_Open_Trial_Search_ID |
37880
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| Preferred_Name |
Enoxaparin Sodium
|
|
| prefixIRI |
NCIT:C75769
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|
| prefLabel |
Enoxaparin Sodium
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| Semantic_Type |
Pharmacologic Substance
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| UMLS_CUI |
C0724579
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| subClassOf |
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