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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C75290
http://purl.obolibrary.org/obo/NCIT_C75290
|
|---|---|
| Preferred Name | Taurultam |
| Definitions |
A reversible metabolite of taurolidine and an amino acid taurine derivative, with antibacterial and antineoplastic activity. Taurultam, like its congener taurolidine, inhibits proliferation of microvascular endothelial cells, although to a lesser extent, by selectively inhibiting the adhesion of endothelial cells to laminin but not to collagen I and fibronectin.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A reversible metabolite of taurolidine and an amino acid taurine derivative, with antibacterial and antineoplastic activity. Taurultam, like its congener taurolidine, inhibits proliferation of microvascular endothelial cells, although to a lesser extent, by selectively inhibiting the adhesion of endothelial cells to laminin but not to collagen I and fibronectin. |
|---|---|
| prefLabel | Taurultam
|
| label | Taurultam
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| code | C75290
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| prefixIRI | NCIT:C75290
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| in_subset | |
| Preferred_Name | Taurultam
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| FDA_UNII_Code | LIX7OM008P
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| Contributing_Source | FDA
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| Chemical_Formula | C3H8N2O2S
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| Maps_To | Taurultam
|
| CAS_Registry | 38668-01-8
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| Legacy Concept Name | Taurultam
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| PubMedID_Primary_Reference |
17395893
9552463
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type | Pharmacologic Substance
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| UMLS_CUI | C0673101
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