Link to this page
Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C74945
http://purl.obolibrary.org/obo/NCIT_C74945
|
|---|---|
| Preferred Name | Vatalanib Succinate |
| Definitions |
The succinate salt of vatalanib, an anilinophthalazine derivative, with antineoplastic activity. Vatalanib binds to and inhibits the protein kinase domain of vascular endothelial growth factor receptors 1 and 2; both receptor tyrosine kinases are involved in angiogenesis. This agent also binds to and inhibits related receptor tyrosine kinases, including platelet-derived growth factor (PDGF) receptor, c-Kit, and c-Fms.
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | The succinate salt of vatalanib, an anilinophthalazine derivative, with antineoplastic activity. Vatalanib binds to and inhibits the protein kinase domain of vascular endothelial growth factor receptors 1 and 2; both receptor tyrosine kinases are involved in angiogenesis. This agent also binds to and inhibits related receptor tyrosine kinases, including platelet-derived growth factor (PDGF) receptor, c-Kit, and c-Fms. |
|---|---|
| prefLabel | Vatalanib Succinate
|
| label | Vatalanib Succinate
|
| code | C74945
|
| Has_Target | |
| prefixIRI | NCIT:C74945
|
| in_subset | |
| Preferred_Name | Vatalanib Succinate
|
| FDA_UNII_Code | V5FUB77031
|
| Contributing_Source | FDA
|
| Chemical_Formula | C20H15ClN4.C4H6O4
|
| Maps_To | Vatalanib Succinate
|
| CAS_Registry | 212142-18-2
|
| Legacy Concept Name | Vatalanib_Succinate
|
| Has_Free_Acid_Or_Base_Form | |
| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type |
Organic Chemical
Pharmacologic Substance
|
| UMLS_CUI | C1524078
|
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |