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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C74093
http://purl.obolibrary.org/obo/NCIT_C74093
|
|---|---|
| Preferred Name | Yttrium Y 90 Anti-CD45 Monoclonal Antibody AHN-12 |
| Definitions |
A radioimmunoconjugate comprised of the monoclonal antibody AHN-12 conjugated to the radioisotope yttrium 90 with potential radioimmunotherapeutic activity. Yttrium Y 90 monoclonal antibody AHN-12 binds to the tyrosine phosphatase CD45, expressed on the surface of normal and malignant hematopoietic cells. After binding and internalization by CD45-expressing tumor cells, this agent may deliver a cytotoxic dose of beta radiation.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A radioimmunoconjugate comprised of the monoclonal antibody AHN-12 conjugated to the radioisotope yttrium 90 with potential radioimmunotherapeutic activity. Yttrium Y 90 monoclonal antibody AHN-12 binds to the tyrosine phosphatase CD45, expressed on the surface of normal and malignant hematopoietic cells. After binding and internalization by CD45-expressing tumor cells, this agent may deliver a cytotoxic dose of beta radiation. |
|---|---|
| prefLabel | Yttrium Y 90 Anti-CD45 Monoclonal Antibody AHN-12
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| label | Yttrium Y 90 Anti-CD45 Monoclonal Antibody AHN-12
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| NCI_META_CUI | CL383503
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| PDQ_Closed_Trial_Search_ID | 587979
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| code | C74093
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| Has_Target | |
| prefixIRI | NCIT:C74093
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| in_subset |
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| Display_Name | Yttrium Y 90 Anti-CD45 Monoclonal Antibody AHN-12
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| Preferred_Name | Yttrium Y 90 Anti-CD45 Monoclonal Antibody AHN-12
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| Contributing_Source | CTRP
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| Maps_To | Yttrium Y 90 Anti-CD45 Monoclonal Antibody AHN-12
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| NCI_Drug_Dictionary_ID | 587979
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| Legacy Concept Name | Yttrium_Y_90_Anti-CD45_Monoclonal_Antibody_AHN-12
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 587979
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| Semantic_Type |
Amino Acid, Peptide, or Protein
Pharmacologic Substance
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