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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C74014
http://purl.obolibrary.org/obo/NCIT_C74014
|
|---|---|
| Preferred Name | Aurora Kinase Inhibitor BI 811283 |
| Definitions |
A small molecule inhibitor of the serine/threonine protein kinase Aurora kinase with potential antineoplastic activity. Aurora kinase inhibitor BI 811283 binds to and inhibits Aurora kinases, resulting in disruption of the assembly of the mitotic spindle apparatus, disruption of chromosome segregation, and inhibition of cell proliferation.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A small molecule inhibitor of the serine/threonine protein kinase Aurora kinase with potential antineoplastic activity. Aurora kinase inhibitor BI 811283 binds to and inhibits Aurora kinases, resulting in disruption of the assembly of the mitotic spindle apparatus, disruption of chromosome segregation, and inhibition of cell proliferation. |
|---|---|
| prefLabel | Aurora Kinase Inhibitor BI 811283
|
| label | Aurora Kinase Inhibitor BI 811283
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| NCI_META_CUI | CL383543
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| PDQ_Closed_Trial_Search_ID | 590640
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| code | C74014
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| prefixIRI | NCIT:C74014
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| in_subset | |
| Preferred_Name | Aurora Kinase Inhibitor BI 811283
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| Maps_To | Aurora Kinase Inhibitor BI 811283
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| NCI_Drug_Dictionary_ID | 590640
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| Legacy Concept Name | Aurora_Kinase_Inhibitor_BI_811283
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 590640
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| Semantic_Type | Pharmacologic Substance
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