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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C74005
http://purl.obolibrary.org/obo/NCIT_C74005
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|---|---|
| Preferred Name | Anti-CD30 Monoclonal Antibody XmAb2513 |
| Definitions |
A humanized monoclonal antibody directed against the cell surface receptor CD30 with potential immunotherapeutic activity. Anti-CD30 monoclonal antibody XmAb2513 specifically binds to the CD30 antigen, which may result in a cytotoxic T lymphocyte (CTL) response against CD30-expressing tumor cells. CD30, a member of the tumor necrosis factor (TNF) receptor superfamily, is expressed on activated lymphocytes transiently and is constitutively expressed in hematologic malignancies including Hodgkin's disease and some T-cell non-Hodgkin's lymphomas.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A humanized monoclonal antibody directed against the cell surface receptor CD30 with potential immunotherapeutic activity. Anti-CD30 monoclonal antibody XmAb2513 specifically binds to the CD30 antigen, which may result in a cytotoxic T lymphocyte (CTL) response against CD30-expressing tumor cells. CD30, a member of the tumor necrosis factor (TNF) receptor superfamily, is expressed on activated lymphocytes transiently and is constitutively expressed in hematologic malignancies including Hodgkin's disease and some T-cell non-Hodgkin's lymphomas. |
|---|---|
| prefLabel | Anti-CD30 Monoclonal Antibody XmAb2513
|
| label | Anti-CD30 Monoclonal Antibody XmAb2513
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| NCI_META_CUI | CL383523
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| PDQ_Closed_Trial_Search_ID | 589299
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| code | C74005
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| Has_Target | |
| prefixIRI | NCIT:C74005
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| in_subset |
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| Display_Name | Anti-CD30 Monoclonal Antibody XmAb2513
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| Preferred_Name | Anti-CD30 Monoclonal Antibody XmAb2513
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| FDA_UNII_Code | 33VWC847G8
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| Contributing_Source |
CTRP
FDA
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| Maps_To | Anti-CD30 Monoclonal Antibody XmAb2513
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| NCI_Drug_Dictionary_ID | 589299
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| Legacy Concept Name | Anti-CD30_Monoclonal_Antibody_XmAb2513
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 589299
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| Semantic_Type | Pharmacologic Substance
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