Link to this page
Biological and Environmental Research Ontology
| Id | http://purl.obolibrary.org/obo/NCIT_C73815
http://purl.obolibrary.org/obo/NCIT_C73815
|
|---|---|
| Preferred Name | Cevipabulin Fumarate |
| Definitions |
The fumarate salt of cevipabulin, a synthetic, water soluble tubulin-binding agent with potential antineoplastic activity. Cevipabulin appears to bind at the vinca-binding site on tubulin, but seems to act more similar to taxane-site binding agents in that it enhances tubulin polymerization and does not induce tubulin depolymerization. The disruption in microtubule dynamics may eventually inhibit cell division and reduce cellular growth., a small, water soluble, synthetic tubulin-binding agent with potential antineoplastic activity. Cevipabulin appears to bind at the vinca-binding site on tubulin, but seems to act more similar to taxane-site binding agents in that it enhances tubulin polymerization and does not induce tubulin depolymerization. The disruption in microtubule dynamics may eventually inhibit cell division and may reduce cellular growth.
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | The fumarate salt of cevipabulin, a synthetic, water soluble tubulin-binding agent with potential antineoplastic activity. Cevipabulin appears to bind at the vinca-binding site on tubulin, but seems to act more similar to taxane-site binding agents in that it enhances tubulin polymerization and does not induce tubulin depolymerization. The disruption in microtubule dynamics may eventually inhibit cell division and reduce cellular growth., a small, water soluble, synthetic tubulin-binding agent with potential antineoplastic activity. Cevipabulin appears to bind at the vinca-binding site on tubulin, but seems to act more similar to taxane-site binding agents in that it enhances tubulin polymerization and does not induce tubulin depolymerization. The disruption in microtubule dynamics may eventually inhibit cell division and may reduce cellular growth. |
|---|---|
| prefLabel | Cevipabulin Fumarate
|
| label | Cevipabulin Fumarate
|
| code | C73815
|
| prefixIRI | NCIT:C73815
|
| in_subset | |
| Preferred_Name | Cevipabulin Fumarate
|
| FDA_UNII_Code | Q380BYV049
|
| Contributing_Source | FDA
|
| Chemical_Formula | C18H18ClF5N6O.C4H4O4.2H2O
|
| Maps_To | Cevipabulin Fumarate
|
| CAS_Registry | 849550-69-2
|
| Legacy Concept Name | Cevipabulin_Fumarate
|
| Has_Free_Acid_Or_Base_Form | |
| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type | Pharmacologic Substance
|
| UMLS_CUI | C2347606
|
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |