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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C73611
http://purl.obolibrary.org/obo/NCIT_C73611
|
|---|---|
| Preferred Name | Bisnafide |
| Definitions |
A bis-naphthalimide compound with anticancer activity. Bisnafide selectively intercalates guanine-cytosine (GC) rich regions of DNA, thereby interfering with DNA replication machinery and activity of topoisomerase II. As a result, this agent causes potent cytotoxicity.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A bis-naphthalimide compound with anticancer activity. Bisnafide selectively intercalates guanine-cytosine (GC) rich regions of DNA, thereby interfering with DNA replication machinery and activity of topoisomerase II. As a result, this agent causes potent cytotoxicity. |
|---|---|
| prefLabel | Bisnafide
|
| label | Bisnafide
|
| Has_Salt_Form | |
| code | C73611
|
| prefixIRI | NCIT:C73611
|
| in_subset | |
| Preferred_Name | Bisnafide
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| FDA_UNII_Code | 62H4W26906
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| Contributing_Source | FDA
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| Chemical_Formula | C32H28N6O8
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| Maps_To | Bisnafide
|
| CAS_Registry | 144849-63-8
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| Legacy Concept Name | Bisnafide
|
| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type | Pharmacologic Substance
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| UMLS_CUI | C0250021
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