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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C72716
http://purl.obolibrary.org/obo/NCIT_C72716
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|---|---|
| Preferred Name | Batabulin |
| Definitions |
A synthetic pentafluorophenylsulfonamide with potential antineoplastic activity. Batabulin covalently binds to beta tubulin, resulting in a disruption of microtubule polymerization, collapse of the cytoskeleton, cell cycle arrest, and tumor cell apoptosis.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A synthetic pentafluorophenylsulfonamide with potential antineoplastic activity. Batabulin covalently binds to beta tubulin, resulting in a disruption of microtubule polymerization, collapse of the cytoskeleton, cell cycle arrest, and tumor cell apoptosis. |
|---|---|
| prefLabel | Batabulin
|
| label | Batabulin
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| Has_Salt_Form | |
| code | C72716
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| prefixIRI | NCIT:C72716
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| in_subset | |
| Preferred_Name | Batabulin
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| FDA_UNII_Code | T4NP8G3K6Q
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| Contributing_Source | FDA
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| Chemical_Formula | C13H7F6NO3S
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| Maps_To | Batabulin
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| CAS_Registry | 195533-53-0
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| Legacy Concept Name | Batabulin
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| type | |
| ALT_DEFINITION | An anticancer drug that belongs to the family of drugs called mitotic inhibitors. It inhibits the growth of cancer cells by preventing cell division.
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| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type | Pharmacologic Substance
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| UMLS_CUI | C0767920
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