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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C71896
http://purl.obolibrary.org/obo/NCIT_C71896
|
|---|---|
| Preferred Name | Motesanib |
| Definitions |
An orally bioavailable receptor tyrosine kinase inhibitor with potential antineoplastic activity. AMG 706 selectively targets and inhibits vascular endothelial growth factor (VEGFR), platelet-derived growth factor (PDGFR), Kit, and Ret receptors, thereby inhibiting angiogenesis and cellular proliferation.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An orally bioavailable receptor tyrosine kinase inhibitor with potential antineoplastic activity. AMG 706 selectively targets and inhibits vascular endothelial growth factor (VEGFR), platelet-derived growth factor (PDGFR), Kit, and Ret receptors, thereby inhibiting angiogenesis and cellular proliferation. |
|---|---|
| prefLabel | Motesanib
|
| label | Motesanib
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| Has_Salt_Form | |
| CHEBI_ID | CHEBI:51098
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| code | C71896
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| prefixIRI | NCIT:C71896
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| in_subset | |
| Preferred_Name | Motesanib
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| FDA_UNII_Code | U1JK633AYI
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| Contributing_Source | FDA
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| Chemical_Formula | C22H23N5O
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| Maps_To | Motesanib
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| CAS_Registry | 453562-69-1
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| Legacy Concept Name | Motesanib
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type | Pharmacologic Substance
|
| UMLS_CUI | C2347295
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| Delete | Subject | Author | Type | Created |
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| No notes to display |