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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C71628
http://purl.obolibrary.org/obo/NCIT_C71628
|
|---|---|
| Preferred Name | Amonafide |
| Definitions |
An imide derivative of naphthalic acid. Amonafide intercalates into DNA and inhibits topoisomerase II, resulting in protein-associated strand breaks and impaired DNA and RNA synthesis.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An imide derivative of naphthalic acid. Amonafide intercalates into DNA and inhibits topoisomerase II, resulting in protein-associated strand breaks and impaired DNA and RNA synthesis. |
|---|---|
| label | Amonafide
|
| prefLabel | Amonafide
|
| Legacy Concept Name | Amonafide_Base
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| in_subset | |
| Preferred_Name | Amonafide
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| Chemical_Formula | C16H17N3O2
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| UMLS_CUI | C0126606
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| FDA_UNII_Code | 1Q8D39N37L
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| prefixIRI | NCIT:C71628
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| Contributing_Source | FDA
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| subClassOf | |
| Has_Salt_Form | |
| code | C71628
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| type | |
| ALT_DEFINITION | A substance that is being studied in the treatment of cancer. It belongs to the families of drugs called topoisomerase inhibitors and intercalating agents.
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| Semantic_Type |
Organic Chemical
Pharmacologic Substance
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| CAS_Registry | 69408-81-7
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| Delete | Subject | Author | Type | Created |
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