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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C71020
http://purl.obolibrary.org/obo/NCIT_C71020
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|---|---|
| Preferred Name | Mucin-16 |
| Definitions |
Mucin-16 (22152 aa, ~2353 kDa) is encoded by the human MUC16 gene. This protein may be involved in both cellular adhesion and the lubrication of mucosal surfaces.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Mucin-16 (22152 aa, ~2353 kDa) is encoded by the human MUC16 gene. This protein may be involved in both cellular adhesion and the lubrication of mucosal surfaces. |
|---|---|
| prefLabel | Mucin-16
|
| label | Mucin-16
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| code | C71020
|
| prefixIRI | NCIT:C71020
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| OMIM_Number | 606154
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| in_subset | |
| Display_Name | Mucin-16
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| Preferred_Name | Mucin-16
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| Contributing_Source | CTRP
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| Swiss_Prot | Q8WXI7
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| Legacy Concept Name | Mucin-16
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| DesignNote | Mucin-16 is a glycoprotein that is synthesized with a single transmembrane domain, and can be proteolytically released from the membrane after intracellular phosphorylation occurs. This protein has been identified as the CA-125 ovarian cancer antigen, which is the basis for a widely used serum assay for the monitoring of patients with ovarian epithelial cancer. This marker cannot detect early ovarian cancer and is not specific enough to be used for population screening. (SwissProt)
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| type | |
| subClassOf | |
| Semantic_Type | Amino Acid, Peptide, or Protein
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| UMLS_CUI | C2347296
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