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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C71011
http://purl.obolibrary.org/obo/NCIT_C71011
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|---|---|
| Preferred Name | Nadofaragene Firadenovec |
| Definitions |
A replication-deficient recombinant adenovirus encoding human interferon alpha-2b with potential antineoplastic activity. Upon intravesical administration, nadofaragene firadenovec infects nearby tumor cells and expresses INF alpha-2b intracellularly which activates the transcription and translation of genes whose products mediate antiviral, antiproliferative, antitumor, and immune-modulating effects.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A replication-deficient recombinant adenovirus encoding human interferon alpha-2b with potential antineoplastic activity. Upon intravesical administration, nadofaragene firadenovec infects nearby tumor cells and expresses INF alpha-2b intracellularly which activates the transcription and translation of genes whose products mediate antiviral, antiproliferative, antitumor, and immune-modulating effects. |
|---|---|
| prefLabel | Nadofaragene Firadenovec
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| label | Nadofaragene Firadenovec
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| NCI_META_CUI | CL376219
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| PDQ_Closed_Trial_Search_ID | 573538
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| code | C71011
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| prefixIRI | NCIT:C71011
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| in_subset |
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| Display_Name | Nadofaragene Firadenove
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| Preferred_Name | Nadofaragene Firadenovec
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| FDA_UNII_Code | 0OOS09O1FH
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| Contributing_Source |
CTRP
FDA
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| Maps_To | Nadofaragene Firadenovec
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| CAS_Registry | 1823059-12-6
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| NCI_Drug_Dictionary_ID | 573538
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| Legacy Concept Name | Recombinant_Adenovirus-Interferon_SCH_721015
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 573538
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| Semantic_Type | Pharmacologic Substance
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