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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Norgestrel | |
| Synonyms |
|
|
| Definitions |
A synthetic progestin commonly used alone or in combination with an estrogen for contraception. Norgestrel suppresses the secretion of luteinizing and follicle-stimulating hormones (LH and FSH), thickens cervical mucus, and slows the transit of ova through the fallopian tubes. This agent also exhibits antiproliferative activity in endometrial tissue and may exhibit chemopreventive and antineoplastic activities in endometrial carcinoma. (NCI04) |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C703 |
|
| Accepted_Therapeutic_Use_For |
Oral contraception
|
|
| CAS_Registry |
6533-00-2
|
|
| CHEBI_ID |
CHEBI:50901 CHEBI:7630
|
|
| Chemical_Formula |
C21H28O2
|
|
| code |
C703
|
|
| Contributing_Source |
CTRP FDA
|
|
| definition |
A synthetic progestin commonly used alone or in combination with an estrogen for contraception. Norgestrel suppresses the secretion of luteinizing and follicle-stimulating hormones (LH and FSH), thickens cervical mucus, and slows the transit of ova through the fallopian tubes. This agent also exhibits antiproliferative activity in endometrial tissue and may exhibit chemopreventive and antineoplastic activities in endometrial carcinoma. (NCI04)
|
|
| Display_Name |
Norgestrel
|
|
| FDA_UNII_Code |
3J8Q1747Z2
|
|
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C176424 http://purl.obolibrary.org/obo/NCIT_C116977 http://purl.obolibrary.org/obo/NCIT_C116978 http://purl.obolibrary.org/obo/NCIT_C128784 |
|
| Is_Value_For_GDC_Property | ||
| label |
Norgestrel
|
|
| Legacy Concept Name |
Norgestrel
|
|
| Maps_To |
Norgestrel
|
|
| NCI_Drug_Dictionary_ID |
39310
|
|
| PDQ_Closed_Trial_Search_ID |
39310
|
|
| PDQ_Open_Trial_Search_ID |
39310
|
|
| Preferred_Name |
Norgestrel
|
|
| prefixIRI |
NCIT:C703
|
|
| prefLabel |
Norgestrel
|
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance
|
|
| UMLS_CUI |
C0028368
|
|
| subClassOf |
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