Biological and Environmental Research Ontology

Last uploaded: December 23, 2022

Id	http://purl.obolibrary.org/obo/NCIT_C693 http://purl.obolibrary.org/obo/NCIT_C693
Preferred Name	Nimustine
Definitions	A nitrosourea with antineoplastic activity. Nimustine alkylates and crosslinks DNA, thereby causing DNA fragmentation, inhibition of protein synthesis, and cell death. (NCI05)
Type	http://www.w3.org/2002/07/owl#Class

definition	A nitrosourea with antineoplastic activity. Nimustine alkylates and crosslinks DNA, thereby causing DNA fragmentation, inhibition of protein synthesis, and cell death. (NCI05)
label	Nimustine
prefLabel	Nimustine
Legacy Concept Name	Nimustine
in_subset	http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C176424 http://purl.obolibrary.org/obo/NCIT_C128784 http://purl.obolibrary.org/obo/NCIT_C157711 http://purl.obolibrary.org/obo/NCIT_C157712 See more See less
Preferred_Name	Nimustine
Is_Value_For_GDC_Property	http://purl.obolibrary.org/obo/NCIT_C1909
Chemical_Formula	C9H13ClN6O2
Maps_To	Nimustine
PDQ_Open_Trial_Search_ID	38853
UMLS_CUI	C0028096
FDA_UNII_Code	0S726V972K
prefixIRI	NCIT:C693
NCI_Drug_Dictionary_ID	38853
Contributing_Source	FDA
subClassOf	http://purl.obolibrary.org/obo/NCIT_C699
Has_Salt_Form	http://purl.obolibrary.org/obo/NCIT_C95325
code	C693
type	http://www.w3.org/2002/07/owl#Class
ALT_DEFINITION	A substance that is being studied in the treatment of brain cancer. It belongs to the family of drugs called nitrosoureas.
NSC Number	245382
PDQ_Closed_Trial_Search_ID	38853
Semantic_Type	Organic Chemical Pharmacologic Substance
CAS_Registry	42471-28-3

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