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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C67087
http://purl.obolibrary.org/obo/NCIT_C67087
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|---|---|
| Preferred Name | Pyruvate Kinase Inhibitor TLN-232 |
| Definitions |
A synthetic cyclic heptapeptide with potential antineoplastic activity. Pyruvate kinase (PK) inhibitor TLN-232 targets pyruvate kinase M2 (M2PK), which may disrupt tumor cell anaerobic glycolysis. M2PK is a dimeric isoform of PK and the predominant PK isoform found in tumor cells
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A synthetic cyclic heptapeptide with potential antineoplastic activity. Pyruvate kinase (PK) inhibitor TLN-232 targets pyruvate kinase M2 (M2PK), which may disrupt tumor cell anaerobic glycolysis. M2PK is a dimeric isoform of PK and the predominant PK isoform found in tumor cells |
|---|---|
| prefLabel | Pyruvate Kinase Inhibitor TLN-232
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| label | Pyruvate Kinase Inhibitor TLN-232
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| PDQ_Closed_Trial_Search_ID | 536241
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| code | C67087
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| prefixIRI | NCIT:C67087
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| in_subset | |
| Preferred_Name | Pyruvate Kinase Inhibitor TLN-232
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| Maps_To | Pyruvate Kinase Inhibitor TLN-232
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| NCI_Drug_Dictionary_ID | 536241
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| Legacy Concept Name | CAP-232
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 536241
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| Semantic_Type | Pharmacologic Substance
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| UMLS_CUI | C0531400
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