Biological and Environmental Research Ontology

Last uploaded: December 23, 2022
Id http://purl.obolibrary.org/obo/NCIT_C67080
http://purl.obolibrary.org/obo/NCIT_C67080
Preferred Name

Eicosapentaenoic Acid
Definitions
An essential, polyunsaturated, 20-carbon omega-3 fatty acid with anti-inflammatory and potential antineoplastic and chemopreventive activities. Eicosapentaenoic acid (EPA) may activate caspase 3, resulting in apoptosis in susceptible tumor cell populations. In addition, this agent may inhibit cyclooxygenase-2 (COX-2), resulting in inhibition of prostaglandin synthesis and prostaglandin-mediated inflammatory processes.
Type http://www.w3.org/2002/07/owl#Class

All Properties

definition

An essential, polyunsaturated, 20-carbon omega-3 fatty acid with anti-inflammatory and potential antineoplastic and chemopreventive activities. Eicosapentaenoic acid (EPA) may activate caspase 3, resulting in apoptosis in susceptible tumor cell populations. In addition, this agent may inhibit cyclooxygenase-2 (COX-2), resulting in inhibition of prostaglandin synthesis and prostaglandin-mediated inflammatory processes.
prefLabel
Eicosapentaenoic Acid
label
Eicosapentaenoic Acid
CHEBI_ID
CHEBI:36006
PDQ_Closed_Trial_Search_ID
537376
Essential_Fatty_Acid
Y
code
C67080
Has_Target
Unit
g
prefixIRI
NCIT:C67080
in_subset
Display_Name
Eicosapentaenoic Acid
Preferred_Name
Eicosapentaenoic Acid
Nutrient
Y
Contributing_Source
CRCH
CTRP
Chemical_Formula
C20H30O2
Maps_To
Eicosapentaenoic Acid
CAS_Registry
25378-27-2
NCI_Drug_Dictionary_ID
537376
Legacy Concept Name
Eicosapentaenoic_Acid
Macronutrient
Y
INFOODS
F20D5
type
ALT_DEFINITION
A class of polyunsaturated fatty acids with 20 carbons and 5 double bonds.
Is_Value_For_GDC_Property
subClassOf
PDQ_Open_Trial_Search_ID
537376
Semantic_Type
Organic Chemical
UMLS_CUI
C0000545
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