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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C66946
http://purl.obolibrary.org/obo/NCIT_C66946
|
|---|---|
| Preferred Name | Aurora Kinase Inhibitor PF-03814735 |
| Definitions |
An aurora kinase inhibitor with potential antineoplastic activity. PF-03814735 binds to and inhibits aurora kinases, serine-threonine kinases that play essential roles in mitotic checkpoint control during mitosis. Inhibition of aurora kinases may result in an inhibition of cellular division and proliferation in tumor cells that overexpress aurora kinases.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An aurora kinase inhibitor with potential antineoplastic activity. PF-03814735 binds to and inhibits aurora kinases, serine-threonine kinases that play essential roles in mitotic checkpoint control during mitosis. Inhibition of aurora kinases may result in an inhibition of cellular division and proliferation in tumor cells that overexpress aurora kinases. |
|---|---|
| prefLabel | Aurora Kinase Inhibitor PF-03814735
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| label | Aurora Kinase Inhibitor PF-03814735
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| PDQ_Closed_Trial_Search_ID | 536035
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| code | C66946
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| prefixIRI | NCIT:C66946
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| in_subset | |
| Preferred_Name | Aurora Kinase Inhibitor PF-03814735
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| FDA_UNII_Code | 6V5T4O5758
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| Contributing_Source | FDA
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| Maps_To | Aurora Kinase Inhibitor PF-03814735
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| CAS_Registry | 942487-16-3
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| NCI_Drug_Dictionary_ID | 536035
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| Legacy Concept Name | PF-03814735
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 536035
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| Semantic_Type | Pharmacologic Substance
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| UMLS_CUI | C1882256
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