Biological and Environmental Research Ontology

Last uploaded: December 23, 2022
Jump to:
Preferred Name

Isoproterenol Sulfate
Synonyms
Definitions

The sulfate salt form of isoproterenol, a beta-adrenergic receptor agonist with bronchodilator activity. Isoproterenol binds to beta-2 adrenergic receptors in bronchial smooth muscle, thereby activating intracellular adenyl cyclase, an enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP levels cause relaxation of bronchial smooth muscle, relieve bronchospasms, improve mucociliary clearance and inhibit the release of mediators of immediate hypersensitivity from cells, especially from mast cells.
ID

http://purl.obolibrary.org/obo/NCIT_C65983
CAS_Registry

6078-56-4
Chemical_Formula

2C11H17NO3.2H2O.H2SO4
code

C65983
Contributing_Source

FDA
definition

The sulfate salt form of isoproterenol, a beta-adrenergic receptor agonist with bronchodilator activity. Isoproterenol binds to beta-2 adrenergic receptors in bronchial smooth muscle, thereby activating intracellular adenyl cyclase, an enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP levels cause relaxation of bronchial smooth muscle, relieve bronchospasms, improve mucociliary clearance and inhibit the release of mediators of immediate hypersensitivity from cells, especially from mast cells.
FDA_UNII_Code

925FX3X776
Has_Free_Acid_Or_Base_Form

http://purl.obolibrary.org/obo/NCIT_C62041
in_subset

http://purl.obolibrary.org/obo/NCIT_C63923
label

Isoproterenol Sulfate
Legacy Concept Name

Isoproterenol_Sulfate
Preferred_Name

Isoproterenol Sulfate
prefixIRI

NCIT:C65983
prefLabel

Isoproterenol Sulfate
Semantic_Type

Pharmacologic Substance
UMLS_CUI

C0282211
subClassOf

http://purl.obolibrary.org/obo/NCIT_C319

http://purl.obolibrary.org/obo/NCIT_C48149
Add comment
Add proposal
Delete Subject Author Type Created
No notes to display