Biological and Environmental Research Ontology

Last uploaded: December 23, 2022
Id http://purl.obolibrary.org/obo/NCIT_C62091
http://purl.obolibrary.org/obo/NCIT_C62091
Preferred Name

Daunorubicin
Definitions
An anthracycline antineoplastic antibiotic with therapeutic effects similar to those of doxorubicin. Daunorubicin exhibits cytotoxic activity through topoisomerase-mediated interaction with DNA, thereby inhibiting DNA replication and repair and RNA and protein synthesis.
Type http://www.w3.org/2002/07/owl#Class

All Properties

definition

An anthracycline antineoplastic antibiotic with therapeutic effects similar to those of doxorubicin. Daunorubicin exhibits cytotoxic activity through topoisomerase-mediated interaction with DNA, thereby inhibiting DNA replication and repair and RNA and protein synthesis.
label
Daunorubicin
prefLabel
Daunorubicin
Legacy Concept Name
Daunorubicin
in_subset
Preferred_Name
Daunorubicin
Is_Value_For_GDC_Property
Chemical_Formula
C27H29NO10
Display_Name
Daunorubicin
Maps_To
Daunorubicin
Has_Target
UMLS_CUI
C0011015
FDA_UNII_Code
ZS7284E0ZP
prefixIRI
NCIT:C62091
Contributing_Source
CTRP
FDA
PCDC
subClassOf
CHEBI_ID
CHEBI:41977
Is_PCDC_AML_Permissible_Value_For_Variable
Has_Salt_Form
code
C62091
type
ALT_DEFINITION
The active ingredient in a drug used to treat acute leukemias and some other types of cancer. It blocks a certain enzyme needed for cell division and DNA repair, and it may kill cancer cells. It is a type of anthracycline antibiotic and a type of topoisomerase inhibitor.
Semantic_Type
Pharmacologic Substance
CAS_Registry
20830-81-3
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