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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Id | http://purl.obolibrary.org/obo/NCIT_C62029
http://purl.obolibrary.org/obo/NCIT_C62029
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|---|---|
| Preferred Name | Flecainide |
| Definitions |
A synthetic agent derived from trifluoroethoxy-benzamide exhibiting antiarrhythmic and local anesthetic activity. As a class Ic antiarrhythmic that blocks sodium channels, flecainide depresses polarization phase 0 and decreases the induction velocity of the His-Purkinje system. It also decreases phase 4 slope and increases the depolarization threshold. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A synthetic agent derived from trifluoroethoxy-benzamide exhibiting antiarrhythmic and local anesthetic activity. As a class Ic antiarrhythmic that blocks sodium channels, flecainide depresses polarization phase 0 and decreases the induction velocity of the His-Purkinje system. It also decreases phase 4 slope and increases the depolarization threshold. (NCI04) |
|---|---|
| label |
Flecainide
|
| prefLabel |
Flecainide
|
| Legacy Concept Name |
Flecainide_Base
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| in_subset | |
| Preferred_Name |
Flecainide
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| Chemical_Formula |
C17H20F6N2O3
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| UMLS_CUI |
C0016229
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| FDA_UNII_Code |
K94FTS1806
|
| prefixIRI |
NCIT:C62029
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| Contributing_Source |
FDA
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| subClassOf | |
| Has_Salt_Form | |
| code |
C62029
|
| type | |
| ALT_DEFINITION |
A drug that is used to treat abnormal heart rhythms. It may also relieve neuropathic pain, the burning, stabbing, or stinging pain that may arise from damage to nerves caused by some types of cancer or cancer treatment.
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| Semantic_Type |
Organic Chemical
Pharmacologic Substance
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| CAS_Registry |
54143-55-4
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