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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Id | http://purl.obolibrary.org/obo/NCIT_C61814
http://purl.obolibrary.org/obo/NCIT_C61814
|
|---|---|
| Preferred Name | Lomefloxacin |
| Definitions |
A synthetic broad-spectrum fluoroquinolone with antibacterial activity. Lomefloxacin inhibits DNA gyrase, a type II topoisomerase involved in the induction or relaxation of supercoiling during DNA replication. This inhibition leads to a decrease in DNA synthesis during bacterial replication, resulting in cell growth inhibition and eventually cell lysis.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A synthetic broad-spectrum fluoroquinolone with antibacterial activity. Lomefloxacin inhibits DNA gyrase, a type II topoisomerase involved in the induction or relaxation of supercoiling during DNA replication. This inhibition leads to a decrease in DNA synthesis during bacterial replication, resulting in cell growth inhibition and eventually cell lysis. |
|---|---|
| label |
Lomefloxacin
|
| prefLabel |
Lomefloxacin
|
| Legacy Concept Name |
Lomefloxacin
|
| in_subset | |
| Preferred_Name |
Lomefloxacin
|
| Chemical_Formula |
C17H19F2N3O3
|
| UMLS_CUI |
C0065162
|
| FDA_UNII_Code |
L6BR2WJD8V
|
| prefixIRI |
NCIT:C61814
|
| Contributing_Source |
FDA
|
| subClassOf | |
| CHEBI_ID |
CHEBI:116278
|
| Has_Salt_Form | |
| code |
C61814
|
| type | |
| Semantic_Type |
Pharmacologic Substance
|
| CAS_Registry |
98079-51-7
|
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