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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C61734
http://purl.obolibrary.org/obo/NCIT_C61734
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|---|---|
| Preferred Name | Docetaxel Anhydrous |
| Definitions |
The anhydrous form of docetaxel, a semisynthetic side-chain analogue of paclitaxel with antineoplastic property. Docetaxel binds specifically to the beta-tubulin subunit of microtubules and thereby antagonizes the disassembly of the microtubule proteins. This results in the persistence of aberrant microtubule structures and results in cell-cycle arrest and subsequent cell death.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | The anhydrous form of docetaxel, a semisynthetic side-chain analogue of paclitaxel with antineoplastic property. Docetaxel binds specifically to the beta-tubulin subunit of microtubules and thereby antagonizes the disassembly of the microtubule proteins. This results in the persistence of aberrant microtubule structures and results in cell-cycle arrest and subsequent cell death. |
|---|---|
| prefLabel | Docetaxel Anhydrous
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| label | Docetaxel Anhydrous
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| CHEBI_ID | CHEBI:4672
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| code | C61734
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| prefixIRI | NCIT:C61734
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| in_subset | |
| Preferred_Name | Docetaxel Anhydrous
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| FDA_UNII_Code | 699121PHCA
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| Contributing_Source | FDA
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| Chemical_Formula | C43H53NO14
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| Maps_To | Docetaxel Anhydrous
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| CAS_Registry | 114977-28-5
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| Legacy Concept Name | Docetaxel_Anhydrous
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type | Pharmacologic Substance
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| UMLS_CUI | C0771375
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