Biological and Environmental Research Ontology

Last uploaded: December 23, 2022
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Id http://purl.obolibrary.org/obo/NCIT_C61612
http://purl.obolibrary.org/obo/NCIT_C61612
Preferred Name

Metformin
Definitions
An agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity. Metformin is associated with a very low incidence of lactic acidosis. This agent helps reduce LDL cholesterol and triglyceride levels, and is not associated with weight gain, and prevents the cardiovascular complications of diabetes. Metformin is not metabolized and is excreted unchanged by the kidneys.
Type http://www.w3.org/2002/07/owl#Class

All Properties

definition

An agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity. Metformin is associated with a very low incidence of lactic acidosis. This agent helps reduce LDL cholesterol and triglyceride levels, and is not associated with weight gain, and prevents the cardiovascular complications of diabetes. Metformin is not metabolized and is excreted unchanged by the kidneys.
label
Metformin
prefLabel
Metformin
Legacy Concept Name
Metformin
in_subset
Preferred_Name
Metformin
Is_Value_For_GDC_Property
Chemical_Formula
C4H11N5
Display_Name
Metformin
Maps_To
Metformin
Has_Target
UMLS_CUI
C0025598
FDA_UNII_Code
9100L32L2N
prefixIRI
NCIT:C61612
Contributing_Source
CTRP
FDA
subClassOf
CHEBI_ID
CHEBI:6801
Has_Salt_Form
code
C61612
type
ALT_DEFINITION
The active ingredient in a drug used to treat diabetes mellitus (a condition in which the body cannot control the level of sugar in the blood). It is also being studied in the treatment of cancer. It decreases the amount of glucose (a type of sugar) released into the bloodstream from the liver and increases the body's use of the glucose. Metformin is a type of antidiabetic agent.
Semantic_Type
Organic Chemical
Pharmacologic Substance
CAS_Registry
657-24-9
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