Link to this page
Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C61501
http://purl.obolibrary.org/obo/NCIT_C61501
|
|---|---|
| Preferred Name | Integrin alpha-2 Inhibitor E7820 |
| Definitions |
A small molecule and aromatic sulfonamide derivative with potential antiangiogenic and antitumor activities. E7820 inhibits angiogenesis by suppressing integrin alpha 2, a cell adhesion molecule expressed on endothelial cells. Inhibition of integrin alpha 2 leads to an inhibition of cell-cell interactions, endothelial cell-matrix interactions, vascular endothelial cell proliferation and angiogenesis.
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A small molecule and aromatic sulfonamide derivative with potential antiangiogenic and antitumor activities. E7820 inhibits angiogenesis by suppressing integrin alpha 2, a cell adhesion molecule expressed on endothelial cells. Inhibition of integrin alpha 2 leads to an inhibition of cell-cell interactions, endothelial cell-matrix interactions, vascular endothelial cell proliferation and angiogenesis. |
|---|---|
| prefLabel | Integrin alpha-2 Inhibitor E7820
|
| label | Integrin alpha-2 Inhibitor E7820
|
| PDQ_Closed_Trial_Search_ID | 363619
|
| code | C61501
|
| Has_Target | |
| prefixIRI | NCIT:C61501
|
| in_subset |
See more
See less
|
| Display_Name | Integrin alpha-2 Inhibitor E7820
|
| Preferred_Name | Integrin alpha-2 Inhibitor E7820
|
| FDA_UNII_Code | TVH5K7949N
|
| Contributing_Source |
CTRP
FDA
|
| Maps_To | Integrin alpha-2 Inhibitor E7820
|
| CAS_Registry | 289483-69-8
|
| NCI_Drug_Dictionary_ID | 363619
|
| Legacy Concept Name | E7820
|
| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 363619
|
| Semantic_Type | Pharmacologic Substance
|
| UMLS_CUI | C1172515
|
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |