Biological and Environmental Research Ontology

Last uploaded: December 23, 2022

Id	http://purl.obolibrary.org/obo/NCIT_C61329 http://purl.obolibrary.org/obo/NCIT_C61329
Preferred Name	Nastorazepide Calcium
Definitions	A selective, orally available, 1,5-benzodiazepine-derivative gastrin/cholecystokinin 2 (CCK-2) receptor antagonist with potential antineoplastic activity. Z-360 binds to the gastrin/CCK-2 receptor, thereby preventing receptor activation by gastrin, a peptide hormone frequently associated with the proliferation of gastrointestinal and pancreatic tumor cells.
Type	http://www.w3.org/2002/07/owl#Class

definition	A selective, orally available, 1,5-benzodiazepine-derivative gastrin/cholecystokinin 2 (CCK-2) receptor antagonist with potential antineoplastic activity. Z-360 binds to the gastrin/CCK-2 receptor, thereby preventing receptor activation by gastrin, a peptide hormone frequently associated with the proliferation of gastrointestinal and pancreatic tumor cells.
prefLabel	Nastorazepide Calcium
label	Nastorazepide Calcium
NCI_META_CUI	CL937292
PDQ_Closed_Trial_Search_ID	485295
code	C61329
prefixIRI	NCIT:C61329
in_subset	http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C176424 http://purl.obolibrary.org/obo/NCIT_C128784 http://purl.obolibrary.org/obo/NCIT_C157711 http://purl.obolibrary.org/obo/NCIT_C157712 See more See less
Preferred_Name	Nastorazepide Calcium
FDA_UNII_Code	GZ3I1DMI8Q
Contributing_Source	FDA
Maps_To	Gastrin/cholecystokinin Type B Receptor Inhibitor Z-360
CAS_Registry	343326-69-2
NCI_Drug_Dictionary_ID	485295
Legacy Concept Name	Z-360
PubMedID_Primary_Reference	17961733
type	http://www.w3.org/2002/07/owl#Class
Is_Value_For_GDC_Property	http://purl.obolibrary.org/obo/NCIT_C1909
subClassOf	http://purl.obolibrary.org/obo/NCIT_C129824
PDQ_Open_Trial_Search_ID	485295
Semantic_Type	Pharmacologic Substance

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